Due to the space-time continuity of the physical attributes, such as temperature and illumination, high spatio-temporal correlation exists among the sensed data in the high-density Wireless Sensor Network (WSN). The data redundancy produced by the correlation brings heavy burden to network communication and shortens the networks lifetime. A Clustered Data Collection Framework (CDCF) based on prediction model was proposed to explore the data correlation and reduce the network traffic. The framework included a time series prediction model based on curve fitting least square method and an efficient error control strategy. In the process of data collection, the clustered structure considered the spatial correlation, and the time series prediction model investigated the temporal correlation existing in sensed data. The experimental simulation proves that CDCF used only 10%—20% of the amount of raw data to finish the data collection of the networks in the relatively stable environment, and the error of the data restored in sink is less than the threshold value which defined by user.